PUBLICATIONS

Kuniaki SAITO Ph.D.

  • Mettl1-dependent m7G tRNA modification is essential for maintaining spermatogenesis and fertility in Drosophila melanogaster.
    Kaneko S, Miyoshi K, Tomuro K, Terauchi M, Tanaka R, Kondo S, Tani N, Ishiguro KI, Toyoda A, Kamikouchi A, Noguchi H, Iwasaki S, Saito K.
    Nat Commun 15(1):8147. (2024) doi: 10.1038/s41467-024-52389-0. PMID: 39317727
  • Lint-O cooperates with L(3)mbt in target gene suppression to maintain homeostasis in fly ovary and brain.
    Hitomi Yamamoto-Matsuda, Keita Miyoshi, Mai Moritoh, Hikari Yoshitane, Yoshitaka Fukada, Kuniaki Saito, Soichiro Yamanaka, Mikiko C Siomi
    EMBO reports 23(10):e53813. (2022) PMID: 35993198
  • Amelioration of a neurodevelopmental disorder by carbamazepine in a case having a gain-of-function GRIA3 variant.
    Kohei Hamanaka, Keita Miyoshi, Jia-Hui Sun, Keisuke Hamada, Takao Komatsubara, Ken Saida, Naomi Tsuchida, Yuri Uchiyama, Atsushi Fujita, Takeshi Mizuguchi, Benedicte Gerard, Allan Bayat, Berardo Rinaldi, Mitsuhiro Kato, Jun Tohyama, Kazuhiro Ogata, Yun Stone Shi, Kuniaki Saito, Satoko Miyatake, Naomichi Matsumoto
    Human genetics 141(2):283-293. (2022) PMID: 35031858
  • Crystal structure of Drosophila Piwi.
    Sonomi Yamaguchi, Akira Oe, Kazumichi M Nishida, Keitaro Yamashita, Asako Kajiya, Seiichi Hirano, Naoki Matsumoto, Naoshi Dohmae, Ryuichiro Ishitani, Kuniaki Saito, Haruhiko Siomi, Hiroshi Nishimasu, Mikiko C Siomi, Osamu Nureki
    Nature communications 11(1) 858-858 (2020) PMID: 32051406
  • Iwasaki YW, Murano K, Ishizu H, Shibuya A, Iyoda Y, Siomi MC, Siomi H, Saito K. Piwi modulates chromatin accessibility by regulating multiple factors including histone H1 to represss transposons.
    Molecular Cell 63: 408-419 (2016) PMID: 27425411
  • Ohtani H, Iwasaki YW, Shibuya A, Siomi H, Siomi MC, Saito K. DmGTSF1 is necessary for Piwi–piRISC-mediated transcriptional transposon silencing in Drosophila.
    Genes Dev 27: 1656-1661 (2013) PMID: 23913921
  • Structure and function of Zucchini endoribonuclease in piRNA biogenesis
    Hiroshi Nishimasu, Hirotsugu Ishizu, Kuniaki Saito, Satoshi Fukuhara, Miharu K. Kamatani, Luc Bonnefond, Naoki Matsumoto, Tomohiro Nishizawa, Keita Nakanaga, Junken Aoki, Ryuichiro Ishitani, Haruhiko Siomi, Mikiko C. Siomi, Osamu Nureki
    Nature 491(7423) 284-7 (2012) PMID: 23064230
  • Saito K, Inagaki S, Mituyama T, Kawamura Y, Ono Y, Sakota E, Kotani H, Asai K, Siomi H, Siomi MC. A regulatory circuit for piwi by traffic jam, a large Maf, in Drosophila gonadal somas.
    Nature 461: 1296-1299 (2009) PMID: 19812547
  • Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells
    Yoshinori Kawamura#, Kuniaki Saito#(#co-first authors), Taishin Kin, Yukiteru Ono, Kiyoshi Asai, Takafumi Sunohara, Tomoko N. Okada, Mikiko C. Siomi, Haruhiko Siomi
    Nature 453(7196) 793-5 (2008) PMID: 18463636
  • A slicer-mediated mechanism for repeat-associated siRNA 5 ‘ end formation in Drosophila
    Lalith S. Gunawardane#, Kuniaki Saito#(#co-first authors), Kazumichi M. Nishida#, Keita Miyoshi, Yoshinori Kawamura, Tomoko Nagami, Haruhiko Siomi, Mikiko C. Siomi
    Science 315(5818) 1587-1590 (2007) PMID: 17322028
  • Mettl1-dependent m7G tRNA modification is essential for maintaining spermatogenesis and fertility in Drosophila melanogaster.
    Kaneko S, Miyoshi K, Tomuro K, Terauchi M, Tanaka R, Kondo S, Tani N, Ishiguro KI, Toyoda A, Kamikouchi A, Noguchi H, Iwasaki S, Saito K.
    Nat Commun 15(1):8147. (2024) doi: 10.1038/s41467-024-52389-0. PMID: 39317727
  • Mod(mdg4) variants repress telomeric retrotransposon HeT-A by blocking subtelomeric enhancers.
    Chikara Takeuchi, Moe Yokoshi, Shu Kondo, Aoi Shibuya, Kuniaki Saito, Takashi Fukaya, Haruhiko Siomi, Yuka W Iwasaki
    Nucleic Acids Res 50(20):11580-11599 (2022) PMID: 36373634
  • Lint-O cooperates with L(3)mbt in target gene suppression to maintain homeostasis in fly ovary and brain.
    Hitomi Yamamoto-Matsuda, Keita Miyoshi, Mai Moritoh, Hikari Yoshitane, Yoshitaka Fukada, Kuniaki Saito, Soichiro Yamanaka, Mikiko C Siomi
    EMBO reports 23(10):e53813. (2022) PMID: 35993198
  • Amelioration of a neurodevelopmental disorder by carbamazepine in a case having a gain-of-function GRIA3 variant.
    Kohei Hamanaka, Keita Miyoshi, Jia-Hui Sun, Keisuke Hamada, Takao Komatsubara, Ken Saida, Naomi Tsuchida, Yuri Uchiyama, Atsushi Fujita, Takeshi Mizuguchi, Benedicte Gerard, Allan Bayat, Berardo Rinaldi, Mitsuhiro Kato, Jun Tohyama, Kazuhiro Ogata, Yun Stone Shi, Kuniaki Saito, Satoko Miyatake, Naomichi Matsumoto
    Human genetics 141(2):283-293. (2022) PMID: 35031858
  • The fifth Japanese meeting on biological function and evolution through interactions between hosts and transposable elements.
    Kenji Ichiyanagi, Kuniaki Saito
    Mobile DNA 13(1) 3 (2022) PMID: 35027075
  • Hamster PIWI proteins bind to piRNAs with stage-specific size variations during oocyte maturation.
    Kyoko Ishino, Hidetoshi Hasuwa, Jun Yoshimura, Yuka W Iwasaki, Hidenori Nishihara, Naomi M Seki, Takamasa Hirano, Marie Tsuchiya, Hinako Ishizaki, Harumi Masuda, Tae Kuramoto, Kuniaki Saito, Yasubumi Sakakibara, Atsushi Toyoda, Takehiko Itoh, Mikiko C Siomi, Shinichi Morishita, Haruhiko Siomi
    Nucleic acids research 49(5) 2700-2720 2021年3月18日 PMID: 33590099
  • Large-Scale Transgenic Drosophila Resource Collections for Loss- and Gain-of-Function Studies.
    Jonathan Zirin, Yanhui Hu, Luping Liu, Donghui Yang-Zhou, Ryan Colbeth, Dong Yan, Ben Ewen-Campen, Rong Tao, Eric Vogt, Sara VanNest, Cooper Cavers, Christians Villalta, Aram Comjean, Jin Sun, Xia Wang, Yu Jia, Ruibao Zhu, Ping Peng, Jinchao Yu, Da Shen, Yuhao Qiu, Limmond Ayisi, Henna Ragoowansi, Ethan Fenton, Senait Efrem, Annette Parks, Kuniaki Saito, Shu Kondo, Liz Perkins, Stephanie E Mohr, Jianquan Ni, Norbert Perrimon
    Genetics 214(4) 755-767 2020年4月 PMID: 32071193
  • Crystal structure of Drosophila Piwi.
    Sonomi Yamaguchi, Akira Oe, Kazumichi M Nishida, Keitaro Yamashita, Asako Kajiya, Seiichi Hirano, Naoki Matsumoto, Naoshi Dohmae, Ryuichiro Ishitani, Kuniaki Saito, Haruhiko Siomi, Hiroshi Nishimasu, Mikiko C Siomi, Osamu Nureki
    Nature communications 11(1) 858 2020年2月12日 PMID: 32051406
  • Nuclear RNA export factor variant initiates piRNA-guided co-transcriptional silencing.
    Kensaku Murano, Yuka W Iwasaki, Hirotsugu Ishizu, Akane Mashiko, Aoi Shibuya, Shu Kondo, Shungo Adachi, Saori Suzuki, Kuniaki Saito, Tohru Natsume, Mikiko C Siomi, Haruhiko Siomi
    EMBO journal 38(17) e102870 2019年9月2日 PMID: 31368590
  • Tango knock-ins visualize endogenous activity of G protein-coupled receptors in Drosophila.
    Hidetaka Katow, Takahiro Takahashi, Kuniaki Saito, Hiromu Tanimoto, Shu Kondo
    J. Neurogenet. 33(2) 44-51 2019年5月14日 PMID: 31084242
  • Tbx6 Induces Nascent Mesoderm from Pluripotent Stem Cells and Temporally Controls Cardiac versus Somite Lineage Diversification.
    Taketaro Sadahiro, Mari Isomi, Naoto Muraoka, Hidenori Kojima, Sho Haginiwa, Shota Kurotsu, Fumiya Tamura, Hidenori Tani, Shugo Tohyama, Jun Fujita, Hiroyuki Miyoshi, Yoshifumi Kawamura, Naoki Goshima, Yuka W Iwasaki, Kensaku Murano, Kuniaki Saito, Mayumi Oda, Peter Andersen, Chulan Kwon, Hideki Uosaki, Hirofumi Nishizono, Keiichi Fukuda, Masaki Ieda
    Cell Stem Cell 23(3) 382-395 2018年9月6日 PMID: 30100166
  • Piwi Modulates Chromatin Accessibility by Regulating Multiple Factors Including Histone H1 to Repress Transposons
    Yuka W. Iwasaki, Kensaku Murano, Hirotsugu Ishizu, Aoi Shibuya, Yumiko Iyoda, Mikiko C. Siomi, Haruhiko Siomi, Kuniaki Saito
    MOLECULAR CELL 63(3) 408-419 2016年8月 PMID: 27425411
  • Inheritance of a Nuclear PIWI from Pluripotent Stem Cells by Somatic Descendants Ensures Differentiation by Silencing Transposons in Planarian
    Norito Shibata, Makoto Kashima, Taisuke Ishiko, Osamu Nishimura, Labib Rouhana, Kazuyo Misaki, Shigenobu Yonemura, Kuniaki Saito, Haruhiko Siomi, Mikiko C. Siomi, Kiyokazu Agata
    DEVELOPMENTAL CELL 37(3) 226-237 2016年5月 PMID: 27165555
  • Small RNA profiling and characterization of piRNA clusters in the adult testes of the common marmoset, a model primate
    Takamasa Hirano, Yuka W. Iwasaki, Zachary Yu-Ching Lin, Masanori Imamura, Naomi M. Seki, Erika Sasaki, Kuniaki Saito, Hideyuki Okano, Mikiko C. Siomi, Haruhiko Siomi
    RNA 20(8) 1223-1237 2014年8月 PMID: 24914035
  • Yb Integrates piRNA Intermediates and Processing Factors into Perinuclear Bodies to Enhance piRISC Assembly
    Yukiko Murota, Hirotsugu Ishizu, Shinichi Nakagawa, Yuka W. Iwasaki, Shinsuke Shibata, Miharu K. Kamatani, Kuniaki Saito, Hideyuki Okano, Haruhiko Siomi, Mikiko C. Siomi
    CELL REPORTS 8(1) 103-113 2014年7月 PMID: 24953657
  • RNAi and overexpression of genes in ovarian somatic cells
    Kuniaki Saito
    Methods in Molecular Biology 1093 25-33 2014年 PMID: 24178554
  • DmGTSF1 is necessary for Piwi-piRISC-mediated transcriptional transposon silencing in the Drosophila ovary
    Hitoshi Ohtani, Yuka W. Iwasaki, Aoi Shibuya, Haruhiko Siomi, Mikiko C. Siomi, Kuniaki Saito
    GENES & DEVELOPMENT 27(15) 1656-1661 2013年8月 PMID: 23913921
  • The epigenetic regulation of transposable elements by PIWI-interacting RNAs in Drosophila
    Kuniaki Saito
    GENES & GENETIC SYSTEMS 88(1) 9-17 2013年2月 PMID: 23676706
  • Structure and function of Zucchini endoribonuclease in piRNA biogenesis
    Hiroshi Nishimasu, Hirotsugu Ishizu, Kuniaki Saito, Satoshi Fukuhara, Miharu K. Kamatani, Luc Bonnefond, Naoki Matsumoto, Tomohiro Nishizawa, Keita Nakanaga, Junken Aoki, Ryuichiro Ishitani, Haruhiko Siomi, Mikiko C. Siomi, Osamu Nureki
    NATURE 491(7423) 279-283 2012年11月 PMID: 23064227
  • Microtubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B
    Yuki Fujiwara, Katsumi Kasashima, Kuniaki Saito, Miho Fukuda, Akira Fukao, Yumi Sasano, Kunio Inoue, Toshinobu Fujiwara, Hiroshi Sakamoto
    BIOCHIMIE 93(5) 817-822 2011年5月 PMID: 21288476
  • Small RNA-Mediated Quiescence of Transposable Elements in Animals
    Kuniaki Saito, Mikiko C. Siomi
    DEVELOPMENTAL CELL 19(5) 687-697 2010年11月 PMID: 21074719
  • Roles for the Yb body components Armitage and Yb in primary piRNA biogenesis in Drosophila
    Kuniaki Saito, Hirotsugu Ishizu, Miharu Komai, Hazuki Kotani, Yoshinori Kawamura, Kazumichi M. Nishida, Haruhiko Siomi, Mikiko C. Siomi
    GENES & DEVELOPMENT 24(22) 2493-2498 2010年11月 PMID: 20966047
  • A microRNA regulatory mechanism of osteoblast differentiation
    Hiroyuki Inose, Hiroki Ochi, Ayako Kimura, Koji Fujita, Ren Xu, Shingo Sato, Makiko Iwasaki, Satoko Sunamura, Yasuhiro Takeuchi, Seiji Fukumoto, Kuniaki Saito, Takashi Nakamura, Haruhiko Siomi, Hiroshi Ito, Yoshiyasu Arai, Ken-ichi Shinomiya, Shu Takeda
    PNAS 106(49) 20794-20799 2009年12月 PMID: 19933329
  • A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila
    Kuniaki Saito, Sachi Inagaki, Toutai Mituyama, Yoshinori Kawamura, Yukiteru Ono, Eri Sakota, Hazuki Kotani, Kiyoshi Asai, Haruhiko Siomi, Mikiko C. Siomi
    NATURE 461(7268) 1296-1299 2009年10月 PMID: 19812547
  • Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences
    Julia Verena Hartig, Stephanie Esslinger, Romy Boettcher, Kuniaki Saito, Klaus Foerstemann
    EMBO JOURNAL 28(19) 2932-2944 2009年10月 PMID: 19644447
  • How selfish retrotransposons are silenced in Drosophila germline and somatic cells
    Mikiko C. Siomi, Kuniaki Saito, Haruhiko Siomi
    FEBS LETTERS 582(17) 2473-2478 2008年7月 PMID: 18572018
  • Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells
    Yoshinori Kawamura, Kuniaki Saito, Taishin Kin, Yukiteru Ono, Kiyoshi Asai, Takafumi Sunohara, Tomoko N. Okada, Mikiko C. Siomi, Haruhiko Siomi
    NATURE 453(7196) 793-U5 2008年6月 PMID: 18463636
  • Gene silencing mechanisms mediated by Aubergine-piRNA complexes in Drosophila male gonad
    Kazumichi M. Nishida, Kuniaki Saito, Tomoko Mori, Yoshinori Kawamura, Tomoko Nagami-Okada, Sachi Inagaki, Haruhiko Siomi, Mikiko C. Siomi
    RNA 13(11) 1911-1922 2007年11月 PMID: 17872506
  • Pimet, the Drosophila homolog of HEN1, mediates 2 ‘-O-methylation of PIWI-interacting RNAs at their 3 ‘ ends
    Kuniaki Saito, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki, Haruhiko Siomi, Mikiko C. Siomi
    GENES & DEVELOPMENT 21(13) 1603-1608 2007年7月 PMID: 17606638
  • A slicer-mediated mechanism for repeat-associated siRNA 5 ‘ end formation in Drosophila
    Lalith S. Gunawardane, Kuniaki Saito, Kazumichi M. Nishida, Keita Miyoshi, Yoshinori Kawamura, Tomoko Nagami, Haruhiko Siomi, Mikiko C. Siomi
    SCIENCE 315(5818) 1587-1590 2007年3月 PMID: 17322028
  • [Novel RNA silencing pathway triggered by Piwi and rasiRNA].
    Saito K, Mikiko CS
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 52(3) 221-226 2007年3月
  • Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome
    Kuniaki Saito, Kazumichi M. Nishida, Tomoko Mori, Yoshinori Kawamura, Keita Miyoshi, Tomoko Nagami, Haruhiko Siomi, Mikiko C. Siomi
    GENES & DEVELOPMENT 20(16) 2214-2222 2006年8月 PMID: 16882972
  • In vitro precursor microRNA processing assays using Drosophila Schneider-2 cell lysates.
    Akira Ishizuka, Kuniaki Saito, Mikiko C Siomi, Haruhiko Siomi
    Methods in molecular biology 342 277-86 2006年 PMID: 16957382
  • Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells.
    Kuniaki Saito, Akira Ishizuka, Haruhiko Siomi, Mikiko C Siomi
    PLoS biology 3(7) e235 2005年7月 PMID: 15918769
  • TAP/NXF1, the primary mRNA export receptor, specifically interacts with a neuronal RNA-binding protein HuD
    K Saito, T Fujiwara, J Katahira, K Inoue, H Sakamoto
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 321(2) 291-297 2004年8月
  • Complex formation of the neuron-specific ELAV-like hu RNA-binding proteins
    K Kasashima, E Sakashita, K Saito, H Sakamoto
    NUCLEIC ACIDS RESEARCH 30(20) 4519-4526 2002年10月

Keita MIYOSHI Ph.D.

  • Elbarbary RA#, Miyoshi K# (#co-first authors), Hedaya, O., Myers, J.R., Maquat L.E. UPF1 helicase promotes TSN-mediated miRNA decay
    Genes & Development, 31: 1483-1493 (2017)
  • Elbarbary RA#, Miyoshi K# (#co-first authors), Myers JR, Du P, Ashton JM, Tian B, Maquat LE. Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1-to-S phase transition. Science, 26: 859-862 (2017)
  • Nishida, KM#, Miyoshi K# (#co-first authors), Ogino A#, Miyoshi T, Siomi MC, Siomi H. Roles of R2D2, a cytoplasmic D2 Body component, in the endogenous siRNA pathway in Drosophila. Molecular Cell 49: 680-691 (2013)
  • Cernilogar FM, Onorati MC, Kothe GO, Burroughs AM, Parsi KM, Breiling A, Sardo FL, Saxena A, Miyoshi K, Siomi H, Siomi MC, Carninci P, Gilmour DS, Corona DFV, Orlando V. Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila. Nature, 480: 391-395 (2011)
  • Miyoshi K, Tsukumo H, Nagami T, Siomi H, Siomi MC. Slicer function of Drosophila Argonautes and its involvement in RISC formation. Genes & Development, 19: 2837-2848 (2005)
  • Kurosaki T, Miyoshi K, Myers JR, Maquat LE. NMD-degradome sequencing reveals ribosome-bound intermediates with 3′-end nontemplated nucleotides. Nature Structural & Molecular Biology (2018) in press
  • Cho H, Rambout X, Gleghorn ML., Nguyen PQT, Phipps CR, Miyoshi K, Myers JR, Kataoka N, Fasan R, Maquat LE. Transcriptional coactivator PGC-1α contains a novel CBP80-binding motif that orchestrates efficient target gene expression. Genes & Development, 32: 555-567 (2018)
  • Lucas BA, Lavi E, Shiue L, Cho H, Katzman S, Miyoshi K, Siomi MC, Carmel L, Ares M Jr., Maquat LE. Evidence for convergent evolution of SINE-directed Staufen-mediated mRNA decay. Proc. Natl. Acad. Sci. USA, 115: 968-973 (2018)
  • Elbarbary RA#, Miyoshi K# (#co-first authors), Hedaya, O., Myers, J.R., Maquat L.E. UPF1 helicase promotes TSN-mediated miRNA decay
    Genes & Development, 31: 1483-1493 (2017)
  • Elbarbary RA#, Miyoshi K# (#co-first authors), Myers JR, Du P, Ashton JM, Tian B, Maquat LE. Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1-to-S phase transition. Science, 26: 859-862 (2017)
  • Nishida, KM#, Miyoshi K# (#co-first authors), Ogino A#, Miyoshi T, Siomi MC, Siomi H. Roles of R2D2, a cytoplasmic D2 Body component, in the endogenous siRNA pathway in Drosophila. Molecular Cell 49: 680-691 (2013)
  • Ueki A, Shimizu T, Masuda K, Yamaguchi SI, Ishikawa T, Sugihara E, Onishi N, Kuninaka S, Miyoshi K, Muto A, Toyama Y, Banno K, Aoki D, Saya H. Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells. PLoS One, 7: e50621. (2012)
  • Cernilogar FM, Onorati MC, Kothe GO, Burroughs AM, Parsi KM, Breiling A, Sardo FL, Saxena A, Miyoshi K, Siomi H, Siomi MC, Carninci P, Gilmour DS, Corona DFV, Orlando V. Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila. Nature, 480: 391-395 (2011)
  • Miyoshi K, Miyoshi T, Hartig JV, Siomi H, Siomi MC. Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and micro RNA biogenesis pathways in Drosophila. RNA, 16: 506-515 (2010)
  • Miyoshi K, Okada TN, Siomi H, Siomi MC. Characterization of miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway. RNA, 15: 1282-1291 (2009)
  • Gunawardane LS, Saito K, Nishida KM, Miyoshi K, Kawamura Y, Nagami T, Siomi H, Siomi MC. A Slicer-mediated mechanism for formation of the 5’ end during rasiRNA biogenesis in Drosophila. Science, 315: 1587-1590 (2007)
  • Saito K, Nishida KM, Mori T, Kawamura Y, Miyoshi K, Nagami T, Siomi H, Siomi MC. Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes & Development, 20: 2214-2222 (2006)
  • Miyoshi K, Tsukumo H, Nagami T, Siomi H, Siomi MC. Slicer function of Drosophila Argonautes and its involvement in RISC formation. Genes & Development, 19: 2837-2848 (2005)
  • Miyoshi K, Shirai C, Horigome C, Takenami K, Kawasaki J, Mizuta K. Rrs1p, a ribosomal protein L11-binding protein, is required for nuclear export of the 60 S pre-ribosomal subunit in Saccharomyces cerevisiae. FEBS letters, 565:106-110 (2004)
  • Miyoshi K, Shirai C, Mizuta K. Transcription of genes encoding trans-acting factors required for rRNA maturation/ribosomal subunit assembly is coordinately regulated with ribosomal protein genes and involves Rap1 in Saccharomyces cerevisiae. Nucleic Acids Research, 31: 1969-1973 (2003)
  • Miyoshi K, Tsujii R, Yoshida H, Maki Y, Wada A, Matsui Y, Toh-e A, Mizuta K. Normal assembly of 60S ribosomal subunits is required for the signaling in response to a secretory defect in Saccharomyces cerevisiae. Journal of Biological Chemistry, 277: 18334-18339 (2002)
  • Morita D, Miyoshi K, Matsui Y, Toh-e A, Shinkawa H, Miyakawa T, Mizuta K. Rpf2p, an evolutionarily conserved protein, interacts with ribosomal protein L11 and is essential for processing of 27SB pre-rRNA to 25S rRNA and 60S ribosomal subunit assembly in Saccharomyces cerevisiae. Journal of Biological Chemistry, 277: 28780-28786 (2002)
  • Miyoshi, K, Miyakawa, T and Mizuta, K. Repression of rRNA synthesis due to a secretory defect requires the C-terminal silencing domain of Rap1p in Saccharomyces cerevisiae. Nucleic Acids Research, 29: 3297-3303 (2001)
  • Tsujii R, Miyoshi K, Tsuno A, Matsui Y, Toh-e A, Miyakawa T, Mizuta K. Ebp2p, yeast homologue of a human protein that interacts with Epstein-Barr virus Nuclear Antigen 1, is required for pre-rRNA processing and ribosomal subunit assembly. Genes to Cells, 5: 543-553 (2000)
  • Tsuno A, Miyoshi K, Tsujii R, Miyakawa T, Mizuta K. RRS1, a conserved essential gene, encodes a novel regulatory protein required for ribosome biogenesis in Saccharomyces cerevisiae. Molecular and Cellular Biology, 20: 2066-2074 (2000)
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